You want to find a drug which inhibits this calcium response pathway in normal cells where it is activated by a signal molecule (red dot). You decide to do mass screening to find that drug. You obtain...

You want to find a drug which inhibits this calcium response pathway in normal cells where it is activated by a signal molecule (red dot). You decide to do mass screening to find that drug. You obtain a large collection of chemical compounds to screen. You make sure that they do not kill the cells and you test them in the following way: you treat the cells with the compounds and then stimulate the cells with the signal molecule (red dot) and analyze the response. Only one compound had an effect you call it drug#1. When the cells are treated with drug#1, and then stimulated with the signal molecule, you find that: 1) cytosolic calcium concentration is low, 2) DAG is not found in membranes, and 3) G-proteins binds GTP normally in drug-treated cells. Give a possible mechanism of action of this drug.

Extracted text: STUDENT NAME: signaling otein coupled receptor (GPCR) signaling pathway: PI 4,5-bisphosphate (PI(4,5)P2] signal molecule activated GPCR activated phospholipase C-B diacylglycerol al rge n. GTP activated protein inositol 1,4,5-trisphosphate (IP) activated G. kinase C Ca 2+ open IP,-gated protein Ca-release channel lumen of endoplasmic reticulum 3) G-proteins binds GTP normally in drug-treated cells. rug.