Which statement is the scientific rationale for administering a proton-pump inhibitor (PPI) to a client diagnosed with gastrointestinal reflux disease (GERD)?  1. PPI medications neutralize the...

Which statement is the scientific rationale for administering a proton-pump inhibitor (PPI) to a client diagnosed with gastrointestinal reflux disease (GERD)?

 1. PPI medications neutralize the gastric secretions. 2. PPI medications block H2 receptors on the parietal cells. 3. PPI medications inhibit the enzyme that generates gastric acid. 4. PPI medications form a protective barrier against acid and pepsin.