Which statement is an advantage of administering the catechol-O-methyltransferase (COMT) inhibitor entacapone (Comtan) to a client diagnosed with Parkinson’s disease?
1. Comtan increases the vasodilating effect of levodopa.
2. Levodopa can be discontinued while the client is taking Comtan.
3. There are no side effects of the drug to interfere with treatment.
4. Comtan causes blood levels of levodopa to be smoother and more sustained.
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