Which of the following is true of the pathophysiology of asthma?
1. Asthma occurs in three phases: the early phase, the intermediate phase, and the late phase.
2. The late phase begins within one to two days of exposure to the trigger and may last for up to approximately a week.
3. The development of an IgE is a strong predisposing factor for developing asthma.
4. Step 1 is the most severe classification category of acute asthma.
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