Which is the most appropriate statement about opioid analgesics? A. In the elderly, tolerance rapidly develops to the constipating effects of morphine. B. An opioid analgesic is the drug of choice for...

Which is the most appropriate statement about opioid analgesics?

A. In the elderly, tolerance rapidly develops to the constipating effects of morphine.

B. An opioid analgesic is the drug of choice for phantom limb pain following a below-knee amputation after a road traffic accident.

C. The analgesic potencies of codeine and dihydrocodeine are similar to that of morphine.

D. Tolerance does not develop to the miotic effect of opioids.

E. Fentanyl can be used for opioid withdrawal and maintenance of the chronically relapsing heroin addict.