Which is the most accurate statement about loop diuretics?
A. They are useful in the treatment of acute pulmonary oedema.
B. They should not be taken together with thiazides.
C. They do not produce hypokalaemia.
D. They increase the hypertonicity of the interstitium in the medullary region.
E. They reduce the risk of ototoxicity with aminoglycoside antibacterial drugs.
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