We can also control for the effect of bilirubin in the PBC mortality data using stratification rather than adjustment. One way to categorize is to create approximately equal-size groups. In Stata, for example, you can categorize by quintile of bilirubin using the command xtile cat5=bilirubin, nq(5). Try fitting a Cox model for cholesterol stratified by bilirubin, stratified at 2, 3, 10, and 50 levels. What is the trade-off in increasing the number of levels? What number of levels works best? (Hint: Balance adjustment against the size of the standard error)
Already registered? Login
Not Account? Sign up
Enter your email address to reset your password
Back to Login? Click here