. Use your PWM from Exercise 5 to simulate 100 lambda operator half-sites, and also simulate 100 non-sites of the same length using iid letters with 50% G+C. Create a PSSM for the simulated...



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Use your PWM from Exercise 5 to simulate 100 lambda operator


half-sites, and also simulate 100 non-sites of the same length using iid letters


with 50% G+C. Create a PSSM for the simulated half-sites. Score the simulated


half-sites and the simulated non-sites, and plot the histograms for each. Select


a cutoff score for discriminating between sites and non-sites, and justify your


choice.





May 05, 2022
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