This two-part assignment will allow you to evaluate the role our genes play in the development of certain diseases. Additionally, you will demonstrate your ability to use electronic database for...

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This two-part assignment will allow you to evaluate the role our genes play in the development of certain diseases. Additionally, you will demonstrate your ability to use electronic database for research purposes.


First, think about your individual health and health risks, by considering what genetic diseases or problems are prevalent in your family. Do you have a predisposition to breast cancer, diabetes, hypertension or any other disease? You may consider your own health risks or those of other individuals such as a family member or friend. Then, in a paper of 750–1,000 words, address the following:



Part I: Evaluating Risk for Disease



  • What genetic diseases or problems did you identify to be potential issues?

  • Choose one of these diseases and provide an introduction of the disease, including the reason why this would be considered to be a genetic/inherited disease?

  • Discuss the major signs/symptoms of the disorder. Research the mode of inheritance for your chosen disease and provide a thorough discussion of the mode of inheritance. If you are not able to find a specific mode of inheritance, provide a hypothesis for the mode of inheritance. Explain your reasoning thoroughly.

  • What information would help an individual who has been recently diagnosed with the disease?

  • What would you say to a family member who is also at risk for developing the disease? What should they know about passing this disease trait to their children?



Part II: Purdue Global Library Search


Finally, visit the library by clicking on My Studies and then selecting the “Library” link on the Campus homepage. Select the option to perform an advanced search by scrolling down to Quick Links and selecting “Advanced Search: EBSCO Discovery Service". Answer the following questions:



  • Search for the disease/trait you selected in Part I of this assignment. What search term(s) did you use?

  • Use a combination of search terms. Which method resulted in the most “hits” or results?

  • What is the difference between this PG library search and a search on a search engine (e.g., Google)?

  • Which search is more appropriate for academic research? Why?

  • Select two credible sources from your Purdue Global Library Search and briefly explain whether these references support or contradict your previous conclusions regarding your selected disease. Please ensure that you have included these sources in your references page. .

Answered Same DayAug 31, 2021

Answer To: This two-part assignment will allow you to evaluate the role our genes play in the development of...

Riyanka answered on Sep 01 2021
154 Votes
Part I: Evaluating Risk for Disease
1. Potential issues – Non-communicable diseases are occurred by genetic mutation. Any mal sequences have seen in genetic disorders. Combination of both factors that is en
vironmental and genetic default may alter chromosomal structure. There are several diseases can be listed as genetic illness for single inheritance like thalassemias, sickle cell anemia, hemochromatosis etc. From multifactorial inheritance heart diseases, arthritis, diabetes, obesity, alzheimer’s disease, breast cancer with changes in chromosome no. 6,11,14,15 etc. As mitochondrial inheritance with Leber's hereditary optic atrophy (LHON), an eye disease and chromosome abnormalities with Down syndrome. From an article by Maria J., Leah M.,  Gerhard H.W. M., and Joanna B. W.(2018). that gene play greater or lesser role in all diseases, variation in DNA function can related with many disease processes. This review explores the genetic basis of human disease, including single gene disorders, chromosomal imbalances, epigenetics, cancer and complex disorders, and considers how our understanding and technological advances can be applied to provision of appropriate diagnosis, management and therapy for patients.
2. One of my cousins suffering in type 1diabetes which is insulin dependence diabetes. Diabetes type l is a genetic disorder characterized by increase in blood sugar, insufficient productivity of insulin. Earlier age of childhood or during adolescence most cases are diagnosis.
HLA is human leukocyte antigen that is related with body immunity cell production and help to distinguish body own proteins to virus or bacteria protein that is foreign. HLA gene includes HLA-DQA1, HLA-DQB1, and HLA-DRB1 like as individual or combination of variation associated with developing type - 1 diabetes. Particularly that combination reduces the immune response to beta cell. Diabetes is auto immune disorder with own body tissues or organs are attacked by immune system. For unknown reasons, in people with type 1 diabetes the immune system damages the...
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