The physician prescribes a maternal blood test for alpha fetoprotein for a nulligravid client at 16 weeks' gestation. When developing the teaching plan, the nurse bases the explanations on the understanding that this test is used to detect which of the following?
1. Neural tube defects.
2. Chromosomal anomalies.
3. Inborn errors of metabolism.
4. Lecithin-sphingomyelin ratio.
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