The nurse should instruct a 21-year-old female client being treated with ampicillin (Principen):
1. To stop taking her oral contraceptives because serious adverse effects could occur.
2. To use oral contraceptives as prescribed because antibiotics do not react with birth control pills.
3. That the antibiotic may decrease the effectiveness of oral contraceptives.
4. That the antibiotic when taken with oral contraceptives causes toxicity.
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