The nurse knows the reason for pretreatment with corticosteroids, antihistamines, and antipyretics prior to the administration of amphotericin B is to:
1. Enhance the effectiveness of this antifungal agent.
2. Eliminate toxic by-products of this antifungal agent.
3. Reduce the severity of adverse effects associated with this antifungal agent.
4. Increase the half-life of this antifungal agent.
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