The nurse is teaching the mother of a 9-year-old child with severe reactive airway disease. The child is prescribed salmeterol (Serevent) by metered dose inhaler (MDI) every 12 hours. Which...

The nurse is teaching the mother of a 9-year-old child with severe reactive airway disease. The child is prescribed salmeterol (Serevent) by metered dose inhaler (MDI) every 12 hours. Which instruction should the nurse include when discussing the medication with the mother?

 1. Instruct the mother to perform and record a daily salmeterol level. 2. Inform the mother to notify the HCP if the child vomits or becomes irritable. 3. Tell the mother to observe the child for a sore throat and respiratory infection. 4. Recommend that the medication be refrigerated at all times.