The nurse is caring for a client who is receiving intravenous vancomycin (Vancocin). Which of the following symptoms, if present, may indicate that the client is experiencing drug-induced ototoxicity?
1. Erythema of the earlobes and ear canal
2. Inner ear pruritus after infusion is completed
3. Tinnitus and high-tone hearing loss
4. Ocular pain with purulent drainage
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