The nurse is caring for a client who has a history of opioid abuse and is monitoring the client for signs of withdrawal. Which manifestations are specifically associated with withdrawal from opioids?
1. Dilated pupils, tachycardia, and diaphoresis
2. Yawning, irritability, diaphoresis, cramps, and diarrhea
3. Tachycardia, hypertension, sweating, and marked tremors
4. Depressed feelings, high drug craving, fatigue, and agitation
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