The male client participating in an investigational protocol calls the clinic and tells the nurse that the medications have made him “sick to my stomach all night.” Which statement is the nurse’s best...

The male client participating in an investigational protocol calls the clinic and tells the nurse that the medications have made him “sick to my stomach all night.” Which statement is the nurse’s best response?

1. “You should consider whether or not you want to be in the study.”

2. “This must be uncomfortable for you. Let’s talk about your feelings.”

3. “Come to the clinic to see the HCP. You may be reacting to the drug.”

4. “This is a temporary problem and will go away with future doses.”