The intensive care nurse is preparing to administer trimetrexate (Neutrexin) to a client diagnosed with AIDS and Pneumocystis carinii pneumonia (PCP). Which interventions should the nurse implement?...

The intensive care nurse is preparing to administer trimetrexate (Neutrexin) to a client diagnosed with AIDS and Pneumocystis carinii pneumonia (PCP). Which interventions should the nurse implement? Select all that apply

1. Administer IV via gravity infusion.

2. Administer concurrently with leucovorin.

3. Monitor the client’s complete blood count.

4. Monitor the client’s liver enzymes.

5. Maintain NPO during drug administration.