The following perifusion data was obtained by Lakey et al. (1996) for canine islets of Langerhans. The islets were challenged with glucose that was initially at 50 mg dL−1 followed by a prompt...

The following perifusion data was obtained by Lakey et al. (1996) for canine islets of Langerhans. The islets were challenged with glucose that was initially at 50 mg dL−1 followed by a prompt increase to 500 mg dL−1. Use the Nomura et al. (1984) islet insulin release model to describe these data.