The drug Clarinex is used to treat symptoms from allergies. In a clinical trial of this drug, 2.1% of the 1655 treated subjects experienced fatigue. Among the 1652 subjects given placebos, 1.2%...

The drug Clarinex is used to treat symptoms from allergies. In a clinical trial of this drug, 2.1% of the 1655 treated subjects experienced fatigue. Among the 1652 subjects given placebos, 1.2% experienced fatigue. Use a 0.05 significance level to test the claim that the incidence of fatigue is greater among those who use Calrinex.

How to construct an appropriate confidence interval?