Answer To: The critique of an epidemiologic study involves an assessment of the methods of data collection...
David answered on Dec 22 2021
Case-Control Study
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Article Citation in APA format:
Lamontagne, F., Garant, M. P., Carvalho, J. C., Lanthier, L., Smieja, M., & Pilon, D. (2008).
Pneumococcal vaccination and risk of myocardial infarction.Canadian Medical Association
Journal, 179(8), 773-777.
Research Question: based on previous laboratory studies it was hypothesized in the research
paper that pneumococcal vaccination would protect patients from myocardial infarction.
Research question is to check if there is association between pneumococcal vaccination and the
risk of myocardial infarction. Also it is studied if any effect of vaccination on the risk of
infarction lessens as time passes.
Health Outcome of Interest: Study population
All the patients who were at risk for myocardial infarction and who were admitted to the between
Jan. 1, 1997, and Dec. 31, 2003wer3e considered for including in study population. Those
patients having parmanent address in the same administrative area as the Centre hospitalier
universitaire de Sherbrooke, were considered for inclusion in study. This hospital is the only
hospital in area with specialized care. We defined risk for myocardial infarction as the presence
of at least one of the following risk factors, as recorded in the patients’ medical records: high
blood pressure, diabetes mellitus or dyslipidemia in men older than 45 years and in women older
than 50 years. Only those patients who had been admitted to one of the hospital’s surgical
departments as orthopedics, gynecology, urology, general surgery, plastic surgery or
otorhinolaryngology were considered for study population.
Exposures of Interest: patients have been considered to be exposed to the pneumococcal
polysaccharide vaccine if they had received this vaccine in the 10 years before the index date, as
recorded in the Logivac database. Exposure has been stratified by the interval between
vaccination and index date.
Diagnostic Criteria for Cases: on the basis of medical records patients with one or more of the
specified cardiovascular risk factors...