The client with rheumatoid arthritis is prescribed the disease-modifying antirheumatic drug (DMARD) methotrexate (Rheumatrex). After 3 days, the client reports that the medication is not working....

The client with rheumatoid arthritis is prescribed the disease-modifying antirheumatic drug (DMARD) methotrexate (Rheumatrex). After 3 days, the client reports that the medication is not working. Which statement is the clinic nurse’s best response?

1. “I will make you an appointment with the health-care provider immediately.”

2. “You are concerned that this medication is not going to work like the other ones.”

3. “Have you lost any more range of motion in your upper extremities?”

4. “That is normal because it takes 3–6 weeks for the medication to work.”