The client with major depressive disorder is prescribed duloxetine (Cymbalta), an atypical antidepressant. The client tells the nurse, “I am going to take my medication at night instead of in the...

The client with major depressive disorder is prescribed duloxetine (Cymbalta), an atypical antidepressant. The client tells the nurse, “I am going to take my medication at night instead of in the morning.” Which statement is the nurse’s best response?

1. “You really should take the medication in the morning for the best results.”

2. “It is all right to take the medication at night. It may help you sleep at night.”

3. “The medication should be taken with food so you should not take it at night.”

4. “Have you discussed taking the medication at night with your psychiatrist?”