The client diagnosed with a pulmonary embolus (PE) is receiving intravenous heparin, and the HCP prescribes 5 mg warfarin (Coumadin) orally once a day. Which statement best explains the scientific rationale for prescribing these two anticoagulants?
1. Coumadin interferes with production of prothrombin.
2. It takes 3–5 days to achieve a therapeutic level of Coumadin.
3. Heparin is more effective when administered with warfarin.
4. Coumadin potentiates the therapeutic action of heparin.
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