The client asks the nurse to explain how colchicine works. The nurse would base the response on which physiological principle? Colchicine: 1. Increases the deposits of uric acid in the synovial spaces...

The client asks the nurse to explain how colchicine works. The nurse would base the response on which physiological principle? Colchicine:

1. Increases the deposits of uric acid in the synovial spaces of the joints.

2. Relieves the pain associated with joint inflammation from gouty arthritis.

3. Prevents the accumulation of uric acid crystals in the joints.

4. Increases renal secretion of uric acid crystals.