The antiarrhythmic action of amiodarone depends only on blockade of K+ channels. 1. Amiodarone reaches steady-state concentrations after several months of treatment. 2. Adenosine is effective in the...

The antiarrhythmic action of amiodarone depends only on blockade of K+ channels.

1. Amiodarone reaches steady-state concentrations after several months of treatment.

2. Adenosine is effective in the treatment of VA.

3. Verapamil affects both the plateau phase 2 and phase 4 of the action potential cycle.

4. Combining verapamil and a β-adrenoceptor antagonist may cause AV nodal conduction block.