The afflicted individuals in the pedigree have dysphasia-like condition. The gel below shows results of PCR amplification of a molecular marker that may be linked to the condition trait. I. |-1 1-2...


The afflicted individuals in the pedigree have dysphasia-like condition. The gel below shows results<br>of PCR amplification of a molecular marker that may be linked to the condition trait.<br>I.<br>|-1 1-2 Il-1 |I-2 |I-3 ||-4 l-1 III-2 III-3 IV-1<br>В<br>I.<br>1<br>4<br>II<br>E<br>1<br>2<br>3<br>A. Based on the evidence, is the molecular marker linked to the condition? In your own words, explain<br>your reasoning.<br>B. What is the mode of inheritance? Explain your reasoning<br>C. Suppose III-3 had a child IV-1 with an afflicted female (no molecular data is available for her).<br>(IV-1 is not indicated in the pedigree, but the molecular data is shown). Based on the data, what is<br>the risk (the chance) that the child IV will have the condition? Explain your reasoning.<br>

Extracted text: The afflicted individuals in the pedigree have dysphasia-like condition. The gel below shows results of PCR amplification of a molecular marker that may be linked to the condition trait. I. |-1 1-2 Il-1 |I-2 |I-3 ||-4 l-1 III-2 III-3 IV-1 В I. 1 4 II E 1 2 3 A. Based on the evidence, is the molecular marker linked to the condition? In your own words, explain your reasoning. B. What is the mode of inheritance? Explain your reasoning C. Suppose III-3 had a child IV-1 with an afflicted female (no molecular data is available for her). (IV-1 is not indicated in the pedigree, but the molecular data is shown). Based on the data, what is the risk (the chance) that the child IV will have the condition? Explain your reasoning.

Jun 10, 2022
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