Answer To: Thalassemia? Thalassemia disease symptoms?
David answered on Dec 26 2021
The symptoms of Thalassemia major generally appear before a child’s second
birthday, the severe anemia related to this condition can be life threatening.
Other symptoms include: Fusinesss, paleness, frequent infections,
poor appetite, failure to thrive,jaundice(yellowing of the skin and whites of the
eyes),enlarged organs.
.. Humans are made up of trillions of cells that form the structure of our bodies
and carry out specialized jobs like taking nutrients from food and turning them into
energy. Red blood cells, which contain hemoglobin, deliver oxygen to all parts of
the body.
The nucleus directs the cell, telling it to grow, mature, divide, or die. The nucleus
contains DNA (deoxyribonucleic acid), a long, spiral-shaped molecule that stores
the genes that determine hair color, eye color, whether or not a person is right- or
left-handed, and many more traits. DNA, along with genes and the information
they contain, is passed down from parents to their children during reproduction.
All cells have a nucleus at their center, which is kind of like the brain or "command
post" of the cell.
Each cell has many DNA molecules, but because cells are very small and DNA
molecules are long, the DNA is packaged very tightly in each cell. These packages
of DNA are called chromosomes, and each cell has 46 of them.
Each package is14 arranged into 23 pairs — with one of each pair coming from
the mother and one from the father. When someone has beta thalassemia, there is a
mutation in chromosome 11.
And each cell has 46 if globin is altered then less beta globin is made. This
effects hemoglobin and decreases the ability of red blood cells to oxygen around
the body.
Peripheral blood stem cell (PBSC) donation is one of two methods of collecting
blood-forming cells for bone marrow transplants.
The same blood-forming cells.that are found in bone marrow are also found in the
circulating (peripheral) blood. For 5 days leading up to your PBSC donation, you
will be given injections of a drug called filgrastim to...