. Suppose that SAGE is used to analyze gene expression from a eukaryote having 30,000 genes each expressed at a level of two transcripts per cell on average. If the average number of ditags per cloned...

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Suppose that SAGE is used to analyze gene expression from a

eukaryote having 30,000 genes each expressed at a level of two transcripts

per cell on average. If the average number of ditags per cloned insert is 20,

what is the least number of clones that must be sequenced to detect, with

probability 0.95, gene expression at a level of 0.5 transcripts/cell? [Hint: This

is a coverage problem. See Section 4.5.]