Suppose that a glutamine residue in the active site of an enzyme was mutated to alanine. As expected, the alanine mutant was inactive, suggesting that the glutamine residue was critical to the...


Suppose that a glutamine residue in the active site of an enzyme was mutated to alanine. As expected, the alanine mutant was<br>inactive, suggesting that the glutamine residue was critical to the catalytic mechanism.<br>Which mutation is most likely to restore wild-type level of activity to the alanine mutant?<br>A to F<br>A to M<br>A to K<br>O A to E<br>A to N<br>

Extracted text: Suppose that a glutamine residue in the active site of an enzyme was mutated to alanine. As expected, the alanine mutant was inactive, suggesting that the glutamine residue was critical to the catalytic mechanism. Which mutation is most likely to restore wild-type level of activity to the alanine mutant? A to F A to M A to K O A to E A to N

Jun 11, 2022
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