Sample Design Literacy In “Cardiovascular Effects of Intravenous Triiodothyronine in Patients Undergoing Coronary Artery Bypass Graft Surgery” [Journal of the American Medical Association (JAMA), Vol. 275, No. 9], the authors explain that patients were assigned to one of three groups: (1) a group treated with triidothyronine, (2) a group treated with normal saline bolus and dopamine, and (3) a placebo group given normal saline. The authors summarize the sample design as “randomized and double-blind.” Describe the meaning of “randomized” and “double-blind” in the context of this study.
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