S. Wang and G. L. Foutch [Chem. Eng. Sci., 46, XXXXXXXXXX)] studied the kinetics of solid-phase peptide synthesis reactions. The stoichiometry of the reactions of interest can be written as A + B ?...

S. Wang and G. L. Foutch [Chem. Eng. Sci., 46, 2373 (1991)] studied the kinetics of solid-phase peptide synthesis reactions. The stoichiometry of the reactions of interest can be written as A + B ? products where A is a symmetrical amino acid anhydride, B a resinsupported peptide containing amino acids, and the products are a resin-supported peptide containing (N + 1) acids, water, and an amino acid. The initial concentration of peptide reactive sites is 0.015 M. The initial mole ratio of the symmetrical anhydride to the peptide reactive sites is 1.5 : 1. It has been suggested that the rate expression is of the mixed second-order form r = k Perform a graphical test to determine if this rate expression is consistent with the following data for the attachment of phenylalanine at position 2 in the synthesis of [Tyr]bradykinin. If the second-order rate expression indicated is consistent with the data, calculate the rate constant at each temperature and the associated activation energy.