RX 351 labs

RX 351 labs


RX 351 Lab - Module 9 Assignment (28pts) Name _______________________________________________________________ Complete and submit on Canvas. You must show all work to receive full credit. Do not leave off units and make sure to use leading zeros. Dropping units in your answer or failure to use a leading zero in an answer will result in no credit for that answer, even if the number itself is correct. 1. (14pts) A patient is receiving LR at 20gtts/min through a 15gtt/ml administration set. a. How many milligrams of sodium chloride and how many milligrams of sodium lactate will this patient receive from this IV fluid in a 24-hour period? b. The Dietary Guidelines for Americans recommends sodium intake of less than 2,300 mg per day—which is equal to about 1 teaspoon of salt. How many “teaspoons of salt” would this patient receive in one 24-hour period from this IV solution? (Na=23, NaCl=58.5; NaLact=112) Circle your answer and show your work. a. ½ tsp b. 1 ½ tsp c. 2 ½ tsp d. 7 ½ tsp c. How many milliequivalents of sodium will the patient receive from this IV fluid in a 24-hour period? d. How many milliequivalents of calcium is the patient receiving over a 24-hour period? (Formula Weight of CaCl2 dihydrate=144) 2. (3pts) A physician orders Magnesium Sulfate 8% to treat a pregnant woman with preeclampsia. Calculate how many milliliters of 50% Magnesium Sulfate Injection USP would need to be added to the bag pictured here to prepare the solution. READ THE LABEL VERY CAREFULLY TO DETERMINE THE CONCENTRATION OF MAG SULFATE. You are adding TO this bag so your total volume is going to be >500ml. Indicate syringe size and round appropriately. 3. (2pts) The solution prepared in Q2 is to be infused at 1g Mag Sulfate/h. Calculate the flow rate (ml/h) for the infusion. 4. (3pts) How many milliequivalents of magnesium would the patient receive every hour? (Mg Sulfate heptahydrate FW=246) 5. (6pts) RxGentamicin sulfate 3.24gE-value =0.05 Sodium bisulfite320mgE-value =0.81 NaOH or HCl qs to adjust to pH ______negligible donation to tonicity Dextrose qs to isotonic E-value =0.16 SWFI qs 100ml Calculate how many milliliters of Dextrose 50% Injection USP (dextrose 50% w/v solution) you would need to make this solution isotonic. 1 RX 351 Lab - Module 9 Assignment (28pts) Name _______________________________________________________________ Complete and submit on Canvas. You must show all work to receive full credit. Do not leave off units and make sure to use leading zeros. Dropping units in your answer or failure to use a leading zero in an answer will result in no credit for that answer, even if the number itself is correct. 1. (14pts) A patient is receiving LR at 20gtts/min through a 15gtt/ml administration set. a. How many milligrams of sodium chloride and how many milligrams of sodium lactate will this patient receive from this IV fluid in a 24-hour period? b. The Dietary Guidelines for Americans recommends sodium intake of less than 2,300 mg per day—which is equal to about 1 teaspoon of salt. How many “teaspoons of salt” would this patient receive in one 24-hour period from this IV solution? (Na=23, NaCl=58.5; NaLact=112) Circle your answer and show your work. a. ½ tsp b. 1 ½ tsp c. 2 ½ tsp d. 7 ½ tsp c. How many milliequivalents of sodium will the patient receive from this IV fluid in a 24-hour period? d. How many milliequivalents of calcium is the patient receiving over a 24-hour period? (Formula Weight of CaCl2 dihydrate=144) 2. (3pts) A physician orders Magnesium Sulfate 8% to treat a pregnant woman with preeclampsia. Calculate how many milliliters of 50% Magnesium Sulfate Injection USP would need to be added to the bag pictured here to prepare the solution. READ THE LABEL VERY CAREFULLY TO DETERMINE THE CONCENTRATION OF MAG SULFATE. You are adding TO this bag so your total volume is going to be >500ml. Indicate syringe size and round appropriately. 3. (2pts) The solution prepared in Q2 is to be infused at 1g Mag Sulfate/h. Calculate the flow rate (ml/h) for the infusion. 4. (3pts) How many milliequivalents of magnesium would the patient receive every hour? (Mg Sulfate heptahydrate FW=246) 5. (6pts) RxGentamicin sulfate 3.24gE-value =0.05 Sodium bisulfite320mgE-value =0.81 NaOH or HCl qs to adjust to pH ______negligible donation to tonicity Dextrose qs to isotonic E-value =0.16 SWFI qs 100ml Calculate how many milliliters of Dextrose 50% Injection USP (dextrose 50% w/v solution) you would need to make this solution isotonic. 1 RX 351 Lab - Module 12 Assignment (38pts) Name _______________________________________________________________ Complete and submit on Canvas. USP 795 is a chapter in the United States Pharmacopeia that sets standards for nonsterile compounding. Use the USP 795 document (provided) to complete this assignment. Part 1 – Personal Preparation 1. (5pts) Pretend you are asked to prepare a compounded formulation for an oral suspension. What would you need to take off (consider what you are currently wearing – including jewelry), and what you need to put on prior to compounding? 2. (5pts) What are the guidelines in USP 795 for hand washing? Part 2 – Selection of Ingredients Read the following information that is on the prescription. Date on Rx: first day of the current month; date dispensed will be day you are completing this worksheet Patient: Jacquelyn Louis Prescriber: Jonas Harris, MD RxMetronidazole 100mg/5ml Oral Suspension Disp. 150ml Sig: 2.5ml po q6h x 14 days; discard remainder No Refills 3. (5pts) You are going to order ingredients to prepare this formulation. What are the standards set by USP 795 for purchasing metronidazole powder (source of API) from a facility within the US? Part 3 – Documentation: To document compounding, you complete a Master Formulation Record (to document the main “recipe”) and a Compounding Record. 4. (3pts) What is the difference between a Master Formulation Record (MFR) and a Compounding Record (CR), in terms of what the purpose of each one serves? 5. (5pts) What information is documented on an MFR but not on a CR? 6. (5pts) What information is documented on a CR but not an MFR? Part 4 – Labeling Prepare a label that will be attached to the patient’s prescription bottle (oval). 7. (10pts) Create the label based on the information in USP 795. Your label must include all information in section 9, unless you do not have access to the information. Use information from USP 795 Section 10 for assigning a beyond-use date and for storage information Any information you are not provided (internal identification # for example or name of compounding facility) you can make up – you will be dispensing this from a community pharmacy so it will be sent outside of your facility. 1