Report about Ebola hemorrhagic fever . Within your report you will: -Include the name of the disease in the title of your report. (1 point) - Describe the signs and symptoms of the disease and...

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Report about
Ebola hemorrhagic fever.


Within your report you will:


-Include the name of the disease in the title of your report. (1 point)
- Describe the signs and symptoms of the disease and indicate where it is normally found and the ways by which it is transmitted. (5 points)
- Name the virus that causes the disease. Indicate the family it belongs to and describe the virus (type of genome, shape, size, enveloped or non-enveloped, components, replication, etc.). Chapter 6 in your textbook and course Module 4 are good sources for how to describe a virus – use these as a guide. This section should be one to two paragraphs.(15 points)
Sources to use as a guide of what to include: Chapter 6 in your textbook and course Module 4 topics: Viral Characteristics, Viral Taxonomy, Viral Structure, Viral Nucleic Acid, and Animal Virus Life Cycle.
-Describe the pathogenesis of infection(how the pathogen infects the host and causes the disease), and how the host's body fights the infection to try and prevent disease.(15 points)
Sources for background information on the pathogenesis of infection: Chapter 18 in your textbook and course Module 4 topic Fate of Viral Infections.
Sources for background information on prevention:Chapter 18 in your textbook and course Module 4 topic Vaccines and Viruses and course Module 5.
-Discuss at least onecurrent (within the past 5 years)scholarly research article on the disease or pathogen. This could include a research study on any one of the following: prevention or treatment of the disease (e.g. new vaccine or drug strategies), diagnosis, prevention of the spread of the pathogen, genetics of the pathogen, host immunity to the pathogen, mechanisms by which the virus can evade or block the host innate antiviral response, or a clinical study.
Include the hypothesis of the research and a summary of the overall approach, the results and conclusion of the authors, and what you found interesting about the research. You may find it helpful to review the Scientific Method Tutorial, Week 1 conference topics, and week 3 and 4 conference activities. (40 points)
- Describe and discuss either environmental or other factors contributing to the emergence or re-emergence of the disease or the impact of the disease on society (locally or globally).(15 points)
- Include a glossary defining the medical and scientific terms that may not be familiar to a student taking this course. (5 points)
- Include in-text citations and a reference page preferably formatted in APA style; be consistent throughout your report. (5 points)
-Use correctgrammar, spelling, punctuation, and sentence and paragraph construction (9 points)
The following criteria will be used when grading your report: the presentation of correct and accurate scientific information, thequality of synthesis and critical thinking,and the adherence to the requirements of the assignment.
You are expected to submityour own work, and your report should be phrased and presented in your own words (no more than 5% of your report is to be directly quoted from your sources).
You must use at least one approved research
article, at least one
book
or textbook (e.g., the course textbook), and at least one
Web site
run by reputable organizations, such as the National Institute of Allergy and Infectious Diseases (NIAID), the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO).
Article
Approved that
must
be used:
http://jid.oxfordjournals.org/content/204/suppl_3/S1043.full?sid=12b72df7-23b8-4b75-9ff5-477440f544c0
Citation: Yen, J. Y., Garamszegi, S., Geisbert, J. B., Rubins, K. H., Geisbert, T. W., Honko, A., . . ., Hensley, L. E. (2011). Therapeutics of Ebola Hemorrhagic Fever: Whole-Genome Transcriptional Analysis of Successful Disease Mitigation.Journal of Infectious Diseases, 204(suppl 3), S1043-S1052. doi:10.1093/infdis/jir345
Book:
Couse book is the following, however,
any other book will do:



















Author:Benjamin S. Weeks
Title:Alcamo's Microbes and Society, 3rd edition, Dec 2010
Publisher:Jones and Bartlett Learning
ISBN:0763790648


Website:

Any
of the ones from the following organization will do:
National Institute of Allergy and Infectious Diseases (NIAID)
Centers for Disease Control and Prevention (CDC)
World Health Organization (WHO).
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Answered Same DayDec 22, 2021

Answer To: Report about Ebola hemorrhagic fever . Within your report you will: -Include the name of the disease...

Robert answered on Dec 22 2021
119 Votes
Running head: EBOLA HEMORRHAGIC FEVER (EHF)
Ebola Hemorrhagic Fever (EHF)
Name:
Professor:
Course:
Date:
2
Ebola Hemorrhagic Fever (EHF)
Ebola Hemorrhagic Fever (EHF)
Introduction
Ebola Hemorrhagic Fever (EHF) can be defined as; a cruel and often fatal disease which
might occur in humans and other primates. Owing to the damaging power (approximately 90%
mortality rate) of this disease, it can be considered a key concern of researchers these days. The
pathogen linked with EHF is Ebola virus which may be called responsible for the development
of diverse signs and symptoms.
Signs and Symptoms
Subsequent signs and symptoms can be identified in the body of a patient during the
incubation period: Arthritis, Chills, Diarrhea, Fever, Headache, Nausea, Sore throat and
Vomiting etc. On the other hand, late symptoms of this illness might involve: Bleeding from
receptors (such as; eyes), mouth and rectum, Depression, Conjunctivitis, Genital swelling,
Hemorrhagic rash, Attacks, Coma, and Delirium (WHO, 2004).
Occurrence and Transmission of disease
Ebola virus might infect people because of their direct contact with blood and/or
secretion(s) of patient. Besides, viral contaminated objects for instance; needles are other chief
reasons of Ebola virus infection. Therefore; this infection can occur in health care settings in a
frequent manner and health-workers could easily become victim of this disease if they do not
follow the standard practices related with health care such as; adoption of safety devices (like;
gloves).
http://www.umm.edu/ency/article/001010.htm
http://www.umm.edu/ency/article/002373.htm
http://www.umm.edu/ency/article/003202.htm
3
Ebola Hemorrhagic Fever (EHF)
Pathogen
Ebola viruses belong to family Filoviridae. Though up to now, the precise source, site,
and natural reservoir of these viruses could not be recognized, yet on the basis of current
evidences, it is believed by researchers that Ebola virus is Zoonotic (animal-borne), and there are
4 to 5 subtypes of it which can be detected in an animal host that is inhabitant of Africa. In fact,
Ebola viruses are enveloped RNA viruses the survival of whom depends on animal reservoirs.
These consist of a molecule of single stranded, negative-sense RNA as their genetic material, and
may be variable in shape for instance, these may appear like “shepherd's crook” or "U" or a "6".
Besides; these viruses might be coiled, toroid, or branched (WHO, 2004).
In terms of dimensions, Ebolavirions are usually 80 nm in width, but can differ up to
some extent in length. Still, the average length of Ebolaviruses varies from 974–1,086 nm and
their maximum length can be up to 14,000 nm. Further, in context of biochemical structure,
Ebolavirions may contain seven structural proteins. Their central part can be covered by a
helical ribonucleocapsid that contains genomic RNA enfolded around a polymer of
nucleoproteins (N P). This ribonucleoprotein can be associated with the RNA-dependent RNA
polymerase (L), polymerase cofactor (VP35), and a transcription activator (VP30). The
ribonucleoprotein remains embedded in a matrix shaped by VP40 and VP24 which are major and
minor matrix proteins respectively. Further, these elements are enclosed by a lipid
membrane generated from host cell membrane. The membrane anchors a glycoprotein (GP)
which projects 7 to 10 nm spikes away from the surface (Baskerville et al., 1978).
Viral life cycle initiates via attachment of virion to particular cell-surface receptors. After
getting attached with the host cell, the envelope of virus may get fused with the membrane, and
can further be followed by release of nucleocapsid of virus into cytosol. Now, RNA polymerase
of virus which...
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