PUBH6005_Assessment Brief 3 Page 1 of 8ASSESSMENT BRIEFSubject Code and Title PUBH6005: EpidemiologyAssessment Assessment 3: Critical Appraisal EssayIndividual/Group IndividualLength 2,500...

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Answered Same DayAug 07, 2021PUBH6005Torrens University Australia

Answer To: PUBH6005_Assessment Brief 3 Page 1 of 8ASSESSMENT BRIEFSubject Code and Title PUBH6005:...

Soumi answered on Aug 10 2021
158 Votes
Running Head: EPIDEMIOLOGY        1
EPIDEMIOLOGY        14
PUBH6005: EPIDEMIOLOGY
ASSESSMENT 3: CRITICAL APPRAISAL ESSAY
(PARTS A & B)
Table of Contents
Part A    3
Research Question    3
Critically Appraisal of Three Articles    3
Article: 1 – A Systematic Review Paper by Costelloe, Metcalfe, Lovering, Mant and Hay (2010)    3
Article: 2 — A Randomised Controlled Trial Paper by Vervloet et al. (2016)    4
Article: 3 — A Qualitative Paper by Sahoo, Tamhankar, Johansson and Lundborg (2010)    5
Part B    7
Introduction    7
Methodology    7
Results    9
Discussion    11
Conclusion    13
References    14
    

Part A
Research Question
How has the use of antibiotics in livestock industry, over-prescription of antibiotics by doctors and incomplete antibiotic courses by patients led to antimicrobial resistance in global public health?
Critically Appraisal of Three Articles
In order to determine the effectiveness of any research article or journal it is necessary to consider some of the aspects. Since, not every article is same as there can be review articles, randomised control trials, cohort studies, qualitative articles and much more therefore; it is necessary to check that whether the research article or journal inculcates all the necessary aspects and follows a recommended format.
Critical Appraisal Skill program (CASP) provides certain checklists for every category of research article or journal and have dynamic set of questions, which can allow checking for the quality of the paper. The current three articles have been tested based on these checklists in order to test for the quality. The serial numbers of each question of each checklist has been mentioned on the left column, while the criticism has been undertaken in the right column.
Article: 1 – A Systematic Review Paper by Costelloe, Metcalfe, Lovering, Mant and Hay (2010)
    Question Number
    Appraisal
    1.
    Yes, the review addresses a clearly focused question.
    2.
    Yes, authors selected observational and experimental studies from Medline, Embase, and Cochrane searches
    3.
    No, some of the studies included were not relevant for this review
    4.
    Yes, MeSH terms were used to identify 4373 papers and further, 2 reviewers assess quality of eligible studies and meta-analysis was performed later.
    5.
    No, results of the review were not combined.
    6.
    Quantities of prescribed antibiotics as well as longer duration of courses were associated with higher rates of resistance.
    7.
    Results are very much précised statistically as well as theoretically along with well-explained conclusion.
    8.
    Yes, results can be applied to local population.
    9.
    Yes, all-important outcomes were considered in this systematic review article.
    10.
    Yes, benefits of the study are worth the harms and costs.
Article: 2 — A Randomised Controlled Trial Paper by Vervloet et al. (2016)
    Question Number
    Appraisal
    1.
    Yes, the trial addresses a clearly focused issue.
    2.
    Yes, the assignment of patients with respiratory tract infection was random.
    3.
    No, all the patients who entered the trial were not properly accounted for in the conclusion.
    4.
    No, patients were not blind to the trial or the treatment.
    5.
    No, there were two different groups; PharmacoTherapy Audit Meetings (PTAM) group that received interventions while other was PharmacoTherapy Audit Meetings (PTAM), which was a matched control group
    6.
    Yes, groups were treated equally and were provided similar attention.
    7.
    The intervention provided to one group was effective in reducing the number of RTI-related antibiotic prescriptions for adolescents and adults and therefore, reducing resistance.
    8.
    The estimate of treatment was not précised.
    9.
    Yes, results can be applied to local population with respiratory tract infections (RTI) easily.
    10.
    Yes, all clinically possible outcomes were considered in this randomised controlled trial.
    11.
    Yes, the benefits were worth the harms and costs.
Article: 3 — A Qualitative Paper by Sahoo, Tamhankar, Johansson and Lundborg (2010)
    Question Number
    Appraisal
    1.
    Yes, there was a clear statement of the aims, which suggested exploring resistant development due to antibiotic use and environmental factors.
    2.
    Yes, qualitative methodology was appropriate.
    3.
    No, the research design was not appropriate to reach the aims and objectives of this study.
    4.
    Yes, the recruitment strategy used was conducting interviews with doctors, drug dispensers and veterinarians, which seem to be appropriate.
    5.
    Yes, the data collected was able to address the issue of this research.
    6.
    The relation between researcher and participants cannot be told if it was adequately considered.
    7.
    Yes, ethical issues such as healthcare behavior, poor professional attitudes, ineffective law enforcement and much more have been considered.
    8.
    No, the data analysis was not sufficiently rigorous
    9.
    Yes, there is a clear statement of findings, which suggest that the two selected themes were interrelated, that is resistance development due to antibiotic use and environmental factors.
    10.
    Research is highly valuable in order to bring focus of authorities and medical professionals towards this concern. Further, there may be a need for education, dissemination and proper law enforcement.
Part B
Introduction
Antibiotics were developed in order to cure infections and diseases caused due to bacterial infestation. These can be used on both animals, humans and these have been proven to be revolutionary in terms of saving human life. However, with the continuous use of these antibiotics, their effect is being diluted that is using similar dosage of same antibiotic repeatedly stays no longer effective later...
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