Problem 5 Sample Size for a Confidence Interval for Two Independent Samples Dichotomous Outcome An investigator wants to estimate the impact of smoking on the incidence of prostate cancer The...

Problem 5

Extracted text: Problem 5 Sample Size for a Confidence Interval for Two Independent Samples Dichotomous Outcome An investigator wants to estimate the impact of smoking on the incidence of prostate cancer The incidence of prostate cancer by the age of 70 is about 1 in 6 (17%) Pz =0. 1 U.S. study reported that heavy smokers had twice the risk of developing prostate cancer as compared to nonsmokers (34%) P6.34 Repeat study in England, cohort enrolls men at age 50 and followed them for 30 years Want to generate a 95% confidence level, assume a 20% attrition, and a margin of error of no more than 0.05 (5%) EFO.0S