The S3’ pocket on PfSUB1 (attached) contains the side chains of Lys465 and Tyr427. Researchers discovered that the Km for substrates with acidic residues in the P3’ position are much lower than those...


The S3’ pocket on PfSUB1 (attached) contains the side chains of Lys465 and Tyr427. Researchers discovered that the Km for substrates with acidic residues in the P3’ position are much lower than those with nonpolar resides at the P3’ position in PfSUB1. Explain the Km data.


p4<br>P2<br>P5'<br>-NH2<br>OH<br>H<br>H<br>H<br>H<br>H<br>он<br>P5<br>P3<br>P2'<br>

Extracted text: p4 P2 P5' -NH2 OH H H H H H он P5 P3 P2'

Jun 11, 2022
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