One of the fascinating use of Genetically modified animals is to produce human antibodies that fight specific pathogens. This passive immunization has the advantage of providing quicker protection, in...


One of the fascinating use of Genetically modified animals is to produce human antibodies that fight specific pathogens. This passive immunization has the advantage of providing quicker protection, in addition to the possibility of protecting immunocompromsed patients, compared to vaccine protective immune response. In the past, producing antibodies to be used by humans was done through immunized animals. This method had the inconvenience of producing mostly polyclonal antibodies, which made the production of monoclonal antibodies difficult and expensive. Genetically engineered cows were the solution to these challenge; and these cows are becoming plasma donors that can save lives of millions of people, including my own life maybe one day. The antibodies they produce could be the golden weapon we can face global outbreaks of infectious diseases like Ebola, influenza, and Zika, with. This potential to address global outbreaks was recognized lately by the World Health Organization (Sparrow et al, 2017); and according to the same report, there were at least 38 monoclonal antibodies products in active clinical trials for 14 infectious diseases like Anthrax, Clostridium botulinum (botulinum neurotoxin A), C difficile, Ebola virus disease, hepatitis B, hepatitis C, Hendra virus, herpes simplex virus, human immunodeficiency virus, influenza, rabies, respiratory syncytial virus. Furthermore, monoclonal antibodies could also be used to face the problem of MDROs and hospital acquired infections. So, do you think like me that GMOs could be the future of infection prevention and control?





Oct 07, 2019
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