Often aerobatic fermentations give off CO2gas because the respiring cells produce CO2as glucose nutrient is converted to chemical energy. The conditions used to set kLafor O2transfer in the fermenter also establish the same hydrodynamic conditions for CO2transfer. Consequently, the transfer rate of CO2from the liquid to the aeration gas is also described by this volumetric mass-transfer coefficient, kLa. Consider that the kLafor O2in the fermenter is 300 h1. Scale the kLa for O2to kLafor CO2transfer using film theory, boundary layer theory, and penetration theory.
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