Many enzymes can hydrolyze GTP between the β and γ phosphates. The GTP analog β,γ-imidoguanosine 5′-triphosphate (Gpp(NH)p), shown below, cannot be hydrolyzed between the β and γ phosphates. Predict...

Many enzymes can hydrolyze GTP between the β and γ phosphates. The GTP analog β,γ-imidoguanosine 5′-triphosphate (Gpp(NH)p), shown below, cannot be hydrolyzed between the β and γ phosphates.

Predict the effect of microinjection of Gpp(NH)p into a myocyte on the cell’s response to β-adrenergic stimulation.

Extracted text: N HN H2N' N. || H|| -0-P-N-P-0-P-0-CH2 H H H. H OH OH Gpp(NH)p (By-imidoguanosine 5'-triphosphate)