Mrs B, aged 43 years, weight 56 kg, requires a loading dose of drug B. The target plasma concentration is 18.9 mg/ L, volume of distribution is 0.5 L/ kg, the salt factor is 0.9 and bioavailability...

Mrs B, aged 43 years, weight 56 kg, requires a loading dose of drug B.  The target plasma concentration is 18.9 mg/ L, volume of distribution is 0.5 L/ kg, the salt factor is 0.9 and bioavailability fraction is 1.

What is the intravenous loading dose (LD) of Drug B in milligrams (mg)?

units - mg