Montelukast inhibits 5-lipoxygenase that converts arachidonic acid to leukotrienes. 1. The LTRA are only given prophylactically. 2. Glucocorticoids reduce eosinophil recruitment to the bronchial...

Montelukast inhibits 5-lipoxygenase that converts arachidonic acid to leukotrienes.

1. The LTRA are only given prophylactically.

2. Glucocorticoids reduce eosinophil recruitment to the bronchial mucosa.

3. Roflumilast is a nonselective inhibitor of PDE isoenzymes.

4. Omalizumab binds to IgE receptors on mast cell membranes, preventing binding of allergen.