· The main idea of the project is to take two articles /papers. Take dataset from one article/paper apply the methods (for analysis) from the other article/paper on the dataset you collected from the...

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Answer To: · The main idea of the project is to take two articles /papers. Take dataset from one article/paper...

Pushpendra answered on Apr 27 2021
136 Votes
Age Of Diagnosis For TCGA Patient by Cancer Type
Abstract
Cancer represents a significant challenge for humankind, as early diagnosis and treatment
are difficult to achieve. BMI was used to categori
ze each person as underweight, normal
weight, overweight or obese. Two- and five-year survival rates were applied to estimate the
prognosis for each cancer type. All data were statistically analyzed. We identified that males
were more susceptible to lung, liver and skin cancer when compared with females, whereas
females were more susceptible to thyroid, breast and adrenal cortex cancer. High BMI (>25)
was positively associated with the occurrence of cancer, although patients with high BMI at
the time of initial diagnosis had higher two/five-year survival rates. The survival rates for
cancer were positively correlated with the age at initial pathologic diagnosis. Some types of
cancer were associated with particularly young ages of onset, including adrenocortical
carcinoma, cervical and endocervical cancers, brain lower grade glioma, pheochromocytoma
and paraganglioma, testicular germ cell tumors and thyroid carcinoma. Hence, the early
diagnosis and prognosis for these cancers need to be improved. In conclusion, sex, BMI and
age are associated with the incidence and survival rates for cancers. These results could be
used to supplement precision and personalized medicine.
Introduction
Cancers are diseases involving the uncontrollable growth of abnormal cells that overcome
the usual limitations to cell division. Cancer is now a relatively common disease. For
example, there were about 90.5 million individuals diagnosed with cancer in 2015 , and
more than 14.1 million new cases of cancer occur each year. Cancer is a leading cause of
death worldwide, accounting for 8.8 million deaths in 2015; 15.7% of all deaths. The most
common causes for cancer-related death are lung, liver, colorectal, stomach and breast
cancers . Cancer is becoming an enormous burden on society in high- and...
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