IT'S MICRONUTRIENT ASSIGNMENT, THE ASSIGNMENT IS MAINLY MULTIPLE CHOICE QUESTION AND VERY FEW QUESTION ANSWERS. I HAVE ATTACHED THE FILE, PLEASE READ THE TIPS WHICH IS WRITTEN IN RED AND DO IT...

Micronutrients – Workshop on Nutritional Genetics: Sem 2, 2017 Nutrigenetics including the relationship between folate status, C677T-MTHFR and spina bifida ONLINE QUESTIONS: You will have organised the data that has been provided into a structured spreadsheet that clearly shows clinical phenotype and genotype. Having read through the material given to you and examined the data; you must now address a number of questions online. This will necessitate significant background reading and research to embrace the wider subject area. The questions as a word doc will be put on Blackboard about one week before the actual quiz goes live. The quiz will stay live for one week. Tips: be very specific with your answers – typos could lose you marks, and there will be no recourse for spelling mistakes. Use lower case throughout – even for names. Also, round all values up if .5 or more, round down if less than .5. Express to the number of decimal places requested. Do not put down units. Question Set 1 – folate status, C677T-MTHFR and spina bifida 1. How many wildtype alleles in the NTD mothers = ? 2. How many polymorphic alleles in the NTD mothers = ? 3. How many wildtype alleles in the control mothers = ? 4. How many polymorphic alleles in the control mothers = ? 5. Use the odds ratio calculator on sheet 2 to calculate the odds ratio for chances of the T allele being associated with NTD pregnancy in this cohort. Odds ratio (to two decimal places) = ? 6. Using the value in 5 above and the 95% CI plus the p value from a chi square test, is the value in 5 significant and hence indicative that the mutant t allele could be a risk factor for NTD (yes/no) = ? 7. PCR stands for = ? 8. The deficiency disease of folic acid is pernicious anaemia (yes/no) = ? 9. The deficiency disease of folic acid is megaloblastic anaemia (yes/no) = ? 10. The deficiency disease of folic acid is a neural tube defect (yes/no) = ? 11. What was the sir name of the Yorkshire academic...