It Must Be a Bad Year for My Allergies
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It is an idyllic March day on the Midwestern university campus as Dr. Bob Johnston walks to his 8:00 philosophy lecture section. As he is walking across campus he notices that his typical spring cough, headache, hoarseness and nasal stuffiness are more noticeable than they have been for the past 7-10 days. As Bob turns the corner towards Old Main he notes that the Dogwoods are beginning to bloom, which confirms his symptoms and reminds him that it is the start of allergy season once again.
As the day progresses Bob notes his prescription antihistamines aren't doing the trick-his head feels unusually full, his voice is unusually hoarse for this time during the day, and he felt slightly nauseous and light-headed. By the completion of office hours Dr. Johnson posts a sign on the door of his office and heads home earlier than normal.
By the start of the next day the symptoms persist, and so Bob calls his physician and asks for an increase in the dosage of his prescribed antihistamine. An appointment is made for the end of the business day. Upon completion of a perfunctory examination Dr. Strangelove writes a prescription for a slightly stronger antihistamine and sends Bob on his way, saying the proverbial "Call me if you don't feel better in a week or so."
Spring semester is coming to a close and the first weekend in May and the accompanying spring commencement is rapidly approaching. En route to a faculty meeting Bob bumps into a departmental colleague that has been on sabbatical and off campus for most of the academic year. John is quite taken aback by Bob's appearance, in that it appears as if Bob has put on weight, especially in the face and neck. Bob states that it has been a horrible spring for his allergies, and the noticeable facial swelling is probably an undesirable side effect of his new prescribed anti-histamine medication. Upon questioning Bob notes that he has wanted to get back in to see his physician but hasn't found the time as he is in the midst of his publisher's various deadlines as Bob prepares a new book on Plato.
Bob awakens that night experiencing chest pain, difficulty in breathing while lying flat, and difficulty in swallowing. He dials 911 and is transported to the local trauma center where he is examined by the chief E.R. resident.
Upon questioning Bob relates his reason for calling the ambulance. In addition he tells the attending physician that he has chest pain, distorted vision, significant hoarseness, headache, nasal stuffiness, nausea and light-headedness.
Patient History:
- Patient is a 5'10", 175-pound 55-year-old-Caucasian male.
- Patient is a smoker and has been since the age of 18. However, in the last year or so, at the advice (nagging?) of his wife he has cut back to less than 1/2 of a pack a day.
- Patient gets little physical exercise other than his daily walk to and from campus, which totals slightly less than 2 miles per day.
Physical Examination:
- HENT examination is normal
- Blood pressure is 140/85 with a resting pulse of 80
- Chest demonstrates slight congestion upon auscultation
- Blood pressure is 145/65 with a resting pulse of 95
- The patient is exhibiting dysphagia, orthopnea and stridor.
- Chest examination by auscultation demonstrates significant congestion.
- The physician confirms significant facial swelling and notes significant swelling in both upper limbs.
- Bending forward and lying down aggravate all of the patient's signs and symptoms.
A chest X-ray and CT scan are ordered for the patient, demonstrating a cavitating right lower pulmonary lobe.
Utilizingsound anatomical logic, consider the following questions:
- The examination of this patient will yield a secondary pathology resulting from another (primary) pathology. What are your diagnoses for both of these pathologies?
- Explain the pathophysiology of the symptoms that initially caused Bob to feel that his allergies were acting up more than normal but ultimately caused him to dial 911.
- One of the possible treatments for Bob's underlying (primary) pathology is surgery. Explain the anatomical considerations the surgeon must take into account as he/she prepares for the patient's surgery.
- What is the lifetime risk of Bob's primary pathology among smokers?