It has been said that we live in a highly volatile, "breach assume" environment. What does "breach assume" mean to a business? Assuming the role of Chief Information Security Officer (CISO), what...

It has been said that we live in a highly volatile, "breach assume" environment.  What does "breach assume" mean to a business?  Assuming the role of Chief Information Security Officer (CISO), what measures would you lead, including technology and policies, to ensure that your company was in a stable breach assume posture?

Be sure to discuss specific tools and technologies, including how they would create a Defense-in-Depth approach.