Is the glucose-sparing effect of growth hormone and glucocorticoids an antagonistic or a synergistic effect? Explain your answer.  How would blocking the activity of phosphodiesterase (PDE) affect a...

Is the glucose-sparing effect of growth hormone and glucocorticoids an antagonistic or a synergistic effect? Explain your answer.

 How would blocking the activity of phosphodiesterase (PDE) affect a cell that responds to hormonal stimulation by the cAMP second messenger system?