In this module, Dr. Anthony Hyman discussed two methods; RNA interference and mass spectrometry following immunoprecipitation. Each of these methods produces different information for analyzing a...

In this module, Dr. Anthony Hyman discussed two methods; RNA interference and mass spectrometry following immunoprecipitation.  Each of these methods produces different information for analyzing a protein’s function or its contribution to a particular complex. What kinds of data can be produced with these techniques alone, versus when the techniques are combined?   And which one should you use to study a protein’s function versus its contribution to a protein complex and why?