In the fruit fly Drosophila, homozygous recessive mutations in the tafazzin gene cause a muscle defect. You want to map the location of tafazzin relative to another gene called vestigial. Homozygous...









Part 1. Given the offspring ratios and genotypes, what must the genotype be of each of the parent flies? Be sure to indicate the HAPLOTYPE of the parents (ie, indicate each chromosome separately) Explain briefly how you got this answer.








In the fruit fly Drosophila, homozygous recessive mutations in the tafazzin gene cause a muscle defect. You want to map the location of tafazzin relative to another gene called<br>vestigial. Homozygous recessive mutations in the vestigial gene result in shriveled wings. Both genes are on autosomes.<br>You cross two parental flies: a heterozygous female and a male homozygous recessive for both genes.<br>The F1 progeny are as follows:<br>155 wild type<br>165 muscle defect, shriveled wings<br>330 muscle defect, normal wings<br>350 normal muscle, shriveled wings<br>Use tz- (for the mutant version of the tafazzin gene), tz+ (for the normal version of the tafazzin gene), vg- (for the mutant version of the vestigial gene), and vg+ (for the normal<br>version of the vestigial gene).<br>

Extracted text: In the fruit fly Drosophila, homozygous recessive mutations in the tafazzin gene cause a muscle defect. You want to map the location of tafazzin relative to another gene called vestigial. Homozygous recessive mutations in the vestigial gene result in shriveled wings. Both genes are on autosomes. You cross two parental flies: a heterozygous female and a male homozygous recessive for both genes. The F1 progeny are as follows: 155 wild type 165 muscle defect, shriveled wings 330 muscle defect, normal wings 350 normal muscle, shriveled wings Use tz- (for the mutant version of the tafazzin gene), tz+ (for the normal version of the tafazzin gene), vg- (for the mutant version of the vestigial gene), and vg+ (for the normal version of the vestigial gene).

Jun 11, 2022
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