I need a reply to 2 of my classmates. 150-200 words for each one. Both are in the attachment below labeled "reply 1" and "reply 2"
Reply #1 Duchenne Muscular Dystrophy Muscular Dystrophy has taken the lives of young children and teens. Many children with this disease do not reach the age of twenty. Unfortunately, this is a X-linked muscle disease by an absence of the protein dystrophin (Sussman, 2002). It is described as a liberal loss of useful muscle mass and replacement with fibrofatty tissue. This deteriorating development begins at birth and ranges throughout the first two decades, by which time patients usually die because of compromise of the respiratory muscular structure. Dystrophin is a protein that helps hold the muscles together and give them strength. Without that muscles are then compromised and causes inflammation, muscle weakness and plenty of damage (Heydemann, 2018). If toddler boys are not walking by the age of eight teen months parents should get them tested for MD (Klinge, 2010). Around the age of four is typically when DMD starts to take its toll. This disease is usually inherited and is passed through the boys of the family. The females are often carriers of the disease. Some symptoms are difficulty walking, jumping, or running, difficulty in getting up from a lying or sitting position, muscle pain and stiffness. Throughout the progression of the disease many things can happen such as heart problems, difficulty breathing, trouble swallowing, inability to walk, and multiple sclerosis. Multiple sclerosis is very common in DMD, about 90% of boys will develop severe sclerosis. Also, walking is stopped by the second decade of life (Sussman,2002). Many patients with this disease are often wheelchair bound. As of now, there is not much treatment for this disease. There are existing remedies, most are dependent upon steroids. It can reduce the symptoms but are incapable of slowing the disease progression. Low exercise such as swimming is recommended to help strengthen muscle. Also, patients can get braces to help with joint stiffness and/or from locking into an uncomfortable position. Boys with severe sclerosis can receive a back surgery to help relieve pain and straighten the spine; the back surgery can also help with breathing troubles. Dr.Heydemann, is one of a number of researchers trying to figure out a way to help strengthen the muscles of patients with DMD. It is very important that we find a way to cure or at least manage this disease. These patients are kids and teenagers, there are supposed to enjoy their life and get the chance to receive a long-lasting life. These children should not have to suffer and should get a chance at a normal childhood. The family members of these children as well should not have to suffer knowing that their children at an early point in their life will pass on. It is extremely difficult, but I say we raise awareness and fund this disease for further research. Reply #2 Osteogenesis imperfecta, or weak bone infection, is an inborn sickness that principally causes low bone mass and bone cracks however it can contrarily influence different organs. (Morello 2018). The illness impacts the skeletal framework, and the fundamental clinical signs are summed up low bone mass, repetitive cracks following a minor injury, bowing of the long bones, vertebral pressure, scoliosis, bone agony, hindered development, and ligamentous and joint laxity (Morello 2018). When it comes to prognosis, I’ve read that it is mainly focused on how severe the osteogenesis is instead of which type or the degree level. In gentle non-distorting OI, analysis is typically cultivated during youth or early pubescence, when cracks for minor injury or bone agony in relationship with low bone mineral thickness happen (Bregou 2016). This disease affects anyone at any age. It can be passed down or the person could just be that one rare person out of 100 who now has Osteogenesis. It affects children, men, and women of any age. With this disease the more severe or physically out of control over mental or physical function, there would be a trained and or professional medical team to monitor and rehabilitate the patients. Some families have in-house nurses to come and take care of the patient, and some will stay in a medical facility to be monitored 24hours. There is no treatment for this disease, but there are surgeries and medications that are aimed to help and decrease the negative effects of Osteogenesis. “Bisphosphonates (a medication mainly used for children) are stored on the outside of the bone. Consequently, treatment plans to expand bone volume by balancing the high turnover cell status of bone in exemplary osteogenesis imperfecta (Forlino 2016).” Some surgeries increase the overall strength of bones that are affected by such a disease. “Using an extending bar in a long bone can balance out an extreme break, offering inside help for mending after rectification of bone deformation. The Fassier-Duval bar intends to be negligibly intrusive, with a solitary section point and doesn't need arthrotomies (Forlino 2016).” Osteogenesis imperfecta is the disease that I chose to give you more information about and for myself as well. I wanted to learn more about this disease because I heard that when women take certain birth controls, it could lead to Osteogenesis imperfecta later down in life. I think that people struggling with this everyday are facing challenges, but they still fight and find a purpose to keep going. If I had the right answers, I think that if a test could be given to a baby to see if they carry certain traits of Osteogenesis, that test could help stop it or increase their bones strength before it could get worse. People should try and focus on this disease because it could impact anyone at any time of their lives. I hope that after you have read this that it has given you more knowledge and also questions on how you can help.