Aim of the Project: To find a scientific paper which has used R tool for analysis. Once we get the paper, we need to: 1.Extract the relevant data sets from the paper in an excel file. 2.Write a R...

I have attached the document and I have explained the key points in the chat box.Flexible with the deadlines


Aim of the Project: To find a scientific paper which has used R tool for analysis. Once we get the paper, we need to: 1.Extract the relevant data sets from the paper in an excel file. 2.Write a R script for these data to reproduce same results like in the paper. I have few papers at my end, topic assigned to me is related to ovary cancer. Please let me know if you could select any of the paper from below and help in doing steps 1 and 2. 1.https://www.nature.com/articles/s41598-019-45165-4 MetaGxData: Clinically Annotated Breast, Ovarian and Pancreatic Cancer Datasets and their Use in Generating a Multi-Cancer Gene Signature 2. https://pubmed.ncbi.nlm.nih.gov/23550061/ CuratedOvarianData: clinically annotated data for the ovarian cancer transcriptome 3. https://pubmed.ncbi.nlm.nih.gov/31940494/ Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment 4. https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(20)30364-9/fulltext BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer 5. https://www.nature.com/articles/s41467-019-11862-x The molecular origin and taxonomy of mucinous ovarian carcinoma 6. https://www.nature.com/articles/s41467-020-15951-0 Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer Note: Papers might look very technical, we can pick up simple things and reproduce a simple analysis from any of the paper. Aim is learning how to rewrite a science paper in R. Else any other suggestion would be helpful. If the tutor finds the paper difficult, I am open to the tutor's suggestions to work on a less complicated paper. But would be great if we can work on something related to ovary cancer research or we can discuss if everything looks difficult, to find a simple cancer paper. Please check this link below and prepare the heat map in the R studio for the data attached in the excel. https://jcoliver.github.io/learn-r/009-expression-heatmaps.html The heatmap should look like this: It has been taken from the paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963791/